ImmuneCarta

Defining the Response™

Study Design and Expert Consultation

ImmuneCarta’s team of Ph.D.-level scientists assist our clients to design immune monitoring strategies aimed at evaluating the efficacy and mechanism of action of novel therapeutics during discovery, pre-clinical and clinical stages of drug development.

Custom-designed studies also include the identification of functional and phenotypic signatures associated with therapeutic efficacy and disease progression. ImmuneCarta’s services are applicable to all therapeutic areas and have already been applied to the following therapeutic areas:

  • Oncology
  • Infectious diseases (Influenza, HIV, HCV)
  • Autoimmunity
  • Allergy

Our team has extensive experience in the design, development, qualification, and validation of 16-color flow cytometry antibody panels and immune monitoring assays for the detection of surface, intracellular, and functional markers such as cytokines and kinases.

ImmuneCarta provides statistical and data analysis services. Our analysis tools are used to identify patterns of phenotypic and functional responses and to quantify the relative distribution of discrete cellular subsets from complex cellular mixtures, including blood and tissues. Interim and final immune monitoring reports include statistical analyses and interpretation of study results.

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